FIGURE 5.

High expression of cytoplasmic protein arginine methyltransferase 5 (cPRMT5) in lung adenocarcinoma is associated with poor patient prognosis. A, Representative histopathologic sections of human adenocarcinoma with high expression of (left) cPRMT5 and (right) nuclear PRMT5 (nPRMT5). Scale bar = 50 μm. B, Kaplan‐Meier analysis of overall survival depending on the cPRMT5 level in lung adenocarcinoma tissues, and the mortality rate and median survival of low and high cPRMT5 expression groups were 24.0% (12/50) and 84.6% (44/52), and 83 and 27 mo, respectively. C, Kaplan‐Meier analysis of overall survival depending on the nPRMT5 level in lung adenocarcinoma tissues, and the mortality rate and median survival of low and high nPRMT5 expression groups were 48.1% (26/54) and 62.5% (30/48), and 83 and 42.5 mo, respectively