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. 2021 Jun 13;112(8):3083–3098. doi: 10.1111/cas.14988

TABLE 2.

Correlation between levels of protein arginine methyltransferase 5 in the cytoplasm (cPRMT5) and nucleus (nPRMT5) with other clinicopathological characteristics in 102 lung adenocarcinomas

Variable Number cPRMT5 nPRMT5
Low expression High expression P‐value Low expression High expression P‐value
Age (y)
≤60 52 22 30 27 25
>60 50 28 22 .167 27 23 .843
Gender
Female 46 27 19 27 19
Male 56 23 33 .076 27 29 .291
Smoking history
Yes 47 27 20 29 18
No 55 23 32 .116 25 30 .101
Tumor location
Left 31 18 13 16 15
Right 71 32 39 .227 38 33 .859
Pathological grade
I‐II 59 34 25 26 33
III 43 16 27 .042* 28 15 .035*
T stage
T1 50 24 26 25 25
T2‐4 52 26 26 .840 29 23 .560
N stage
N0 59 37 22 35 24
N1‐3 43 13 30 .001** 19 24 .130
M stage
M0 99 50 49 52 47
M1 3 0 3 .243 2 1 1.000
TNM stage
I‐II 71 45 26 38 33
III‐IV 31 5 26 <.001** 16 15 .859
Mortality
Survived 46 38 8 28 18
Died 56 12 44 <.001** 26 30 .146
*

P <. 05; **<.005.