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IC50 (nmol/L) of VLX1570 in leukemia cell lines
| IC50 (nmol/L) | 24 h | 48 h |
|---|---|---|
| HL‐60 | 20.5 ± 0.3 | 19.0 ± 0.8 |
| MOLM13 | 38.0 ± 1.0 | 32.2 ± 0.6 |
| MV4‐11 | 43.1 ± 0.2 | 37.9 ± 2.1 |
| OCI‐AML3 | 52.2 ± 0.8 | 38.4 ± 2.1 |
| THP‐1 | 29.1 ± 1.7 | 24.0 ± 0.6 |
| K562 | 340.8 ± 15.1 | 184.7 ± 8.6 |
| MDS‐L | 21.8 ± 0.5 | 21.4 ± 0.6 |
| F‐36P | 52.4 ± 1.1 | 46.3 ± 2.8 |
| MOLT‐4 | 30.6 ± 0.9 | 28.9 ± 0.3 |
| Jurkat | 55.9 ± 2.8 | 37.9 ± 1.5 |
| U937 | 38.2 ± 1.2 | 31.4 ± 2.1 |
