FIGURE 6.

Regulation of cell proliferation by FZD5 in Epstein‐Barr virus (EBV)‐positive gastric cancer (GC). A, Knockdown experiments were performed using two different siRNAs (siFZD5#1 and #2) in MKN7_EB, SNU719, YCC10, and NCC24. The FZD5 expression level was determined by RT‐qPCR. GAPDH was used as a normalized control for the RT‐qPCR assay. B, Growth assays in FZD5 knockdown cells. FZD5 knockdown significantly inhibited cell proliferation in EBV‐positive GC. C, Growth assays in STAT3 knockdown cells. STAT3 knockdown significantly inhibited cell proliferation in EBV‐positive GC