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. Author manuscript; available in PMC: 2023 Oct 26.
Published in final edited form as: J Med Chem. 2021 Aug 4;65(4):2880–2904. doi: 10.1021/acs.jmedchem.1c00598

Figure 5.

Figure 5.

X-ray co-crystal structures of compounds 19 and 21, select residues are shown as sticks with key hydrogen bonds shown as dashes. A) 19 in complex with SC2 3CLpro (PDB: 7LMD); B) 21 in complex with SC2 3CLpro (PDB: 7LMF)