TABLE 4.
Predictors of cognitive, disability, HRQL and motor change in multivariate analysis (model using battery of separate non‐motor symptom scales)
| MoCA | Cognitive state | Disability | HRQL | Motor function | |||
|---|---|---|---|---|---|---|---|
| Parameter estimate (95% CI) | P | Parameter estimate (95% CI) | P | ||||
| Age | – | – | – | – | |||
| Age of onset | – | – | – | – | |||
| Gender | – | – | – | – | |||
| Hoehn and Yahr stage | 0.302 (0.104 to 0.876) | 0.028 | NS | NS | |||
| UPDRS III total | NS | NS | NS | NS | |||
| MoCA | – | – | NS | NS | |||
| RBDSQ | – | – | – | – | |||
| HADS ‐ anxiety | – | – | – | – | |||
| HADS ‐ depression | – | – | NS | NS | |||
| SCOPA‐sleep daytime | – | – | – | – | |||
| SCOPA‐sleep night‐time | – | – | NS | NS | |||
| PPQ | 0.800 (0.626 to 1.022) | 0.074 | NS | NS | |||
| Apathy | – | – | NS | NS | |||
| EQ‐index | – | – | |||||
| EQ‐VAS | NS | NS | −0.003 (−0.006 to 0.0004) | 0.071 | |||
| UPDRS II | NS | NS | NS | NS | |||
| Schwab and England | NS | NS | −0.008 (−0.013 to −0.003) | 0.001 | |||
UPDRS: Unified Parkinson's Disease Rating Scale MoCA, Montreal Cognitive Assessment scale; RBDSQ, REM Sleep Behavioral Disorder Symptom Questionnaire; HADS, Hospital Anxiety and Depression Scale, SCOPA, Scale for Outcomes in Parkinson's Disease; PPQ, Parkinson's Psychosis Questionnaire; EQ, EuroQol.