Fig. 1.

Contrast-enhanced ultrasound perfusion imaging with VueBox® (Bracco, Italy) of a small histopathologically proven hepatocellular carcinoma. a Irregular arterial hypervascularization in the tumor center and at the tumor margin with wash-out beginning in the portal venous phase. b False colors for parametric imaging: red and yellow for the tumor hyperenhancement. c Evaluation of the wash-in rate. d Numeric values of the TIC analysis (c), VueBox® Screenshot with permission of Bracco Imaging, Italy