Fig. 4.

a Fusion contrast-enhanced ultrasound with magnetic resonance imaging (left) and perfusion imaging (CEUS, right) of a small histopathologically proven prostate cancer. Irregular arterial hypervascularization at the tumor margin with wash-out beginning in the venous phase. b Dynamic curve analysis up to 60 s. False colors for parametric imaging, red and yellow for the tumor hyperenhancement. Evaluation of the peak enhancement with highest level (green) on the peripheral part (green circle)