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. 2021 Aug 10;10(4):2415–2429. doi: 10.1007/s40121-021-00516-5

Table 2.

Clinical outcomes of patients with ventilator-associated pneumonia due to S. maltophilia receiving tigecycline or fluoroquinolones

Outcomes All Tigecycline Fluoroquinolones p
Overall analysis
 Clinical cure (n = 82) 38 (46.3%) 15 (32.6%) 23 (63.9%) 0.009
 Microbiological cure (n = 57) 23 (40.4%) 10 (28.6%) 13 (59.1%) 0.045
 28-Day mortality (n = 82) 32 (39%) 22 (47.8%) 10 (27.8%) 0.105
Subgroup analysis by excluding P. aeruginosa co-infection
 Clinical cure (n = 72) 35 (48.6%) 14 (35%) 21 (65.6%) 0.019
 28-Day mortality (n = 72) 30 (41.7%) 21 (52.5%) 9 (28.1%) 0.065
Subgroup analysis by excluding appropriate initial antibiotic therapy
 Clinical cure (n = 70) 30 (42.9%) 15 (32.6%) 15 (62.5%) 0.032
 28-Day mortality (n = 70) 27 (38.6%) 22 (47.8%) 5 (20.8%) 0.052