Table 2.
Clinical outcomes of patients with ventilator-associated pneumonia due to S. maltophilia receiving tigecycline or fluoroquinolones
| Outcomes | All | Tigecycline | Fluoroquinolones | p |
|---|---|---|---|---|
| Overall analysis | ||||
| Clinical cure (n = 82) | 38 (46.3%) | 15 (32.6%) | 23 (63.9%) | 0.009 |
| Microbiological cure (n = 57) | 23 (40.4%) | 10 (28.6%) | 13 (59.1%) | 0.045 |
| 28-Day mortality (n = 82) | 32 (39%) | 22 (47.8%) | 10 (27.8%) | 0.105 |
| Subgroup analysis by excluding P. aeruginosa co-infection | ||||
| Clinical cure (n = 72) | 35 (48.6%) | 14 (35%) | 21 (65.6%) | 0.019 |
| 28-Day mortality (n = 72) | 30 (41.7%) | 21 (52.5%) | 9 (28.1%) | 0.065 |
| Subgroup analysis by excluding appropriate initial antibiotic therapy | ||||
| Clinical cure (n = 70) | 30 (42.9%) | 15 (32.6%) | 15 (62.5%) | 0.032 |
| 28-Day mortality (n = 70) | 27 (38.6%) | 22 (47.8%) | 5 (20.8%) | 0.052 |