Skip to main content
. 2021 Mar 25;16(11):2276–2283. doi: 10.4103/1673-5374.310696

Figure 7.

Figure 7

Effects of functional scaffolds on the inflammatory cells and CSPGs levels in the injured spinal cord.

(A) A diagram showing sampling sites in a longitudinal section of injured spinal cord. (B1–B3) IBA-1-positive cells (white arrows) in the rostral (B1), injury/graft (B2) and caudal (B3) sites of spinal cord in the DON group. (C1–C3) IBA-1-positive cells (white arrows) in the rostral (C1), injury/graft (C2) and caudal (C3) sites in the CS group. (D1–E3) CSPGs immunofluorescence in longitudinal sections of the injured spinal cord. Fewer IBA-1-positive cells and lower CSPGs expression were found in the DON group compared with the CS group. Scale bars: 30 µm in B1–E3. (F) Number of IBA-1-positive cells in the DON and CS groups. (G) Level of CSPGs in the DON and CS groups. The data are presented as mean ± SD (n = 5). *P < 0.05, vs. CS (one-way analysis of variance followed by the least statistical difference test). CS: Collagen sponge; CSPGs: chondroitin sulfate proteoglycans; DON: decellularized optic nerve; HOE: Hoechst 33342; IBA-1: ionized calcium binding adaptor molecule 1.