TABLE 1.

Advantages and disadvantages of mRNA vaccines.

Advantage	Disadvantage
Rapid research and development, simple production process	mRNA is unstable and easily degraded
mRNA vaccines do not require nuclear localization signals and transcription in vivo	Strong immunogenicity, triggering unnecessary immune response
No risk of integration into host DNA	Safety is lower than inactivated vaccines
Effectiveness is higher than inactivated vaccines	Effectiveness is lower than DNA vaccines

mRNA vaccines: how we show up.