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. 2021 Jul 27;11:718731. doi: 10.3389/fonc.2021.718731

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Copyright © 2021 Chen, Xie, Liu, Liu, Li, Zhang, Zhang, Wang, Zhang, Sun and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-142a may act as a suppressor in CML progression. (A) Schematic of miR-142a treatment on BA-induced CML mice. (B) Follow-up analysis of the PB white blood cell (WBC) count after transplantation. (C) Follow-up analysis of the proportion of mCherry⁺ cells in PB. (D) Immunophenotype analysis of mice in BA and BA+miR-142a group. (E) Kaplan-Meier survival curve of mice inoculated with miR-142a overexpression or control lentivirus. Results are mean ± SEM, p value was assessed by unpaired t-test.