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Impaired in vitro differentiation of erythroid precursors from CD4C/HIV Tg micea
| BM progenitor | Stroma | No. of BFU-E |
|---|---|---|
| Non-Tg | Non-Tg | 49 ± 7 |
| Tg | 54 ± 6 | |
| Non-Tg/Tg | 51 ± 5 | |
| Tg | Non-Tg | 0 |
| Tg | 0 | |
| Non-Tg/Tg | 0 |
BM cells from control and CD4C/HIVMutA Tg mice were incubated with hydrocortisone (10−6 M) in the presence of stromal cells from non-Tg or Tg mice either alone or mixed (non-Tg/Tg) (1:1) and BFU-E colonies counted.
