Table 1.

Description of the variants analysed in the genetic test

Risk of hyperinflammation
Gene	Polymorphism	Patient’s alleles	Comments	Reference
1. TNF	rs1799724	CT	Allele T: related to increased levels of TNFα	Mlak et al20
2. TNF	rs1800693	CC	Allele C: related to the higher incidence of inflammatory diseases	De Jager et al21
3. IL-6	rs1800795	CG	G allele: related to increased levels of IL-6	Tartter et al22
4. IL-6	rs1800796	GG	G allele: related to increased levels of IL-6	Bull et al23

Some variants are related to the increased risk of inflammation. The numbering alleles 1, 2, 3 and 4 showed higher risk of inflammation.

IL, interleukin; TNFα, tumour necrosis factor alpha.