Table 4 Variance analysis comparison (T1 vs. T3) of the 2 preeclampsia groups.
Control group (n = 15) | Intervention group (n = 14) | Variance analysis p (η p 2 )/observed power | |||||||
---|---|---|---|---|---|---|---|---|---|
T1° | T3° | d | T1° | T3° | d | Group | Time | Group × time | |
The data are given as ° mean ± standard deviation and significant differences are shown in bold. d = effect size; significance level: p < 0.05 and η p 2 ≥ 0.10, d ≥ 0.50 and observed power ≥ 0.80 AIx: augmentation index; AoPP: aortic pulse pressure; CO: cardiac output; MAP: mean arterial pressure; T: measurement time; BP: blood pressure; SEVR: subendocardial viability ratio; SV: stroke volume | |||||||||
Primary outcome | |||||||||
aPWV (m/s) | 7.83 ± 1.64 | 7.33 ± 2.25 | 0.54 | 7.20 ± 1.11 | 6.36 ± 0.76 | 0.90 | 0.095 (0.100)/0.386 | 0.072 (0.115)/0.439 | 0.632 (0.009)/0.075 |
Secondary outcomes | |||||||||
pPWV (m/s) | 16.0 ± 9.78 | 11.4 ± 3.80 | 0.68 | 11.7 ± 2.78 | 10.1 ± 1.82 | 0.70 | 0.069 (0.118)/0.448 | 0.045 (0.140) /0.526 | 0.311 (0.038)/0.169 |
AIx (%) | 22.5 ± 9.27 | 15.7 ± 7.29 | 0.82 | 21.1 ± 13.4 | 15.8 ± 5.99 | 0.55 | 0.815 (0.002)/0.056 | 0.015 (0.200) /0.707 | 0.741 (0.004)/0.062 |
AoPP (mmHg) | 58.0 ± 7.92 | 46.0 ± 8.09 | 1.50 | 55.4 ± 11.1 | 42.7 ± 5.88 | 1.50 | 0.266 (0.046)/0.195 | < 0.001 (0.643)/1.000 | 0.824 (0.002)/0.055 |
CO (l/min) | 7.23 ± 1.67 | 5.76 ± 1.10 | 1.06 | 7.16 ± 1.66 | 5.30 ± 1.01 | 1.39 | 0.543 (0.014)/0.091 | < 0.001 (0.555)/1.000 | 0.493(0.018)/0.103 |
SEVR (%) | 127 ± 38.7 | 150 ± 22.2 | 0.76 | 133 ± 24.0 | 156 ± 23.5 | 1.00 | 0.438 (0.022)/0.118 | 0.003 (0.280)/0.878 | 0.951(0.000)/0.050 |
SV (ml) | 88.8 ± 13.1 | 76.4 ± 9.52 | 1.10 | 85.3 ± 12.5 | 71.7 ± 10.0 | 1.21 | 0.283 (0.043)/0.184 | < 0.001 (0.609)/1.000 | 0.760 (0.004)/0.060 |
syst. BP (mmHg) | 148 ± 10.2 | 127 ± 13.7 | 1.76 | 148 ± 15.5 | 117 ± 9.11 | 2.52 | 0.231 (0.053)/0.219 | < 0.001 (0.788)/1.000 | 0.095 (0.100)/0.386 |
diast. BP (mmHg) | 83.7 ± 9.30 | 73.7 ± 8.40 | 1.13 | 85.4 ± 8.85 | 68.5 ± 6.29 | 2.23 | 0.483 (0.018)/0.105 | < 0.001 (0.653)/1.000 | 0.081 (0.108)/0.416 |
Pulse pressure (mmHg) | 64.6 ± 8.93 | 52.9 ± 7.43 | 1.43 | 63.5 ± 10.8 | 48.8 ± 7.06 | 1.65 | 0.338 (0.035)/0.156 | < 0.001 (0.653)/1.000 | 0.436 (0.024)/0.119 |
MAP (mmHg) | 114 ± 8.72 | 97.4 ± 11.7 | 1.63 | 116 ± 9.50 | 90.4 ± 8.66 | 2.82 | 0.368 (0.031)/0.143 | < 0.001 (0.798)/1.000 | 0.058 (0.131)/0.480 |
Performance at lactate threshold 2 mmol/l (W) | – | – | – | 51.6 ± 10.6 | 60.1 ± 18.1 | 0.59 | – | 0.013 (0.388) /0.756 | – |