Table 2.

Clinical and histopathological differences between acute necrotising mucormycosis and chronic granulomatous mucormycosis (adopted from Vinay et al.[13])

	Acute necrotising mucormycosis	Chronic granulomatous mucormycosis
Onset	Acute	Chronic
Progression	Rapid	Slow
Cellular immunity	Usually impaired	Usually intact
Causative organism	Rhizopus, Mucor	Rhizomucor
Mode of involvement	Traumatic inoculation, Haematogenous dissemination, Contiguous spread	Traumatic inoculation
Clinical features	Reddish purple indurated plaques progressing to necrosis and eschar formation	Erythematous plaque with a progressive margin and areas of healing and scar formation
Angioinvasion	Present	Absent
Histolopathology	Necrotising inflammation	Granulomatous inflammation
Treatment	Control of predisposing condition, surgical debridement and liposomal amphotericin B	Liposomal amphotericin B
Prognosis and mortality	Poor can lead to mortality	Good, no mortality but causes significant morbidity