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. 2021 Aug 10;16(8):e0255796. doi: 10.1371/journal.pone.0255796

Fig 2. Longitudinal analysis of IgG subclasses of antibody responses to RBD in COVID-19 patients.

Fig 2

Dynamic changes in RBD-specific IgG subclasses including IgG1 (A), IgG2 (B), IgG3 (C) and IgG4 (D) antibody response in individual COVID-19 patients (N = 15). Data are plotted by antibody response calculated as the ratio between OD of uncoated and coated antigen wells of an individual sample. Each line represents an individual subject. Solid line and square symbol represent pneumonia cases. Dot line and triangle symbol represent mild cases.