Skip to main content
. 2021 Aug 10;16(8):e0256023. doi: 10.1371/journal.pone.0256023

Table 4. Covariates associated with death by Cox survival analysis.

Variables Univariate Analysis Multivariate Analysis
HR 95% CI p HR 95% CI P
Age (years) 1.01 0.99–1.03 0.068 1.01 1.00–1.03 0.035
Male gender 1.46 1.01–2.11 0.042 1.47 1.04–2.09 0.029
Diabetes mellitus 1.55 1.03–2.32 0.034 1.51 1.06–2.17 0.022
Hypertension 0.94 0.62–1.43 0.797
Cerebrovascular disease 1.90 1.11–3.26 0.019 1.82 1.08–3.07 0.023
Malignancy 1.12 0.70–1.78 0.631
Oxygen saturation in room air at hospital admission (<90%) 1.25 0.68–2.29 0.463
eGFR in previous year (ml/min/1.73m2) 0.99 0.99–1.00 0.402
Serum albumin (g/L) 0.74 0.54–1.03 0.082 0.74 0.54–1.01 0.064
CRP (>20-fold x ULN) 0.88 0.61–1.26 0.494
LDH (>2-fold x ULN) 1.45 0.95–2.20 0.079 1.55 1.05–2.30 0.027
Lymphocyte count (mm3) 1.00 1.00–1.00 0.708
Thrombocyte count (mm3) 0.99 0.99–1.00 0.047 0.99 0.99–1.00 0.052
AKI stage 1 (ref)
    AKI stage 2 1.85 1.15–2.98 0.011 1.98 1.25–3.14 0.003
    AKI stage 3 2.19 1.40–3.43 <0.001 2.25 1.44–3.51 <0.001

CRP, C-reactive protein; LDH, lactate dehydrogenase.