Table 4. Covariates associated with death by Cox survival analysis.
Variables | Univariate Analysis | Multivariate Analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | P | |
Age (years) | 1.01 | 0.99–1.03 | 0.068 | 1.01 | 1.00–1.03 | 0.035 |
Male gender | 1.46 | 1.01–2.11 | 0.042 | 1.47 | 1.04–2.09 | 0.029 |
Diabetes mellitus | 1.55 | 1.03–2.32 | 0.034 | 1.51 | 1.06–2.17 | 0.022 |
Hypertension | 0.94 | 0.62–1.43 | 0.797 | |||
Cerebrovascular disease | 1.90 | 1.11–3.26 | 0.019 | 1.82 | 1.08–3.07 | 0.023 |
Malignancy | 1.12 | 0.70–1.78 | 0.631 | |||
Oxygen saturation in room air at hospital admission (<90%) | 1.25 | 0.68–2.29 | 0.463 | |||
eGFR in previous year (ml/min/1.73m2) | 0.99 | 0.99–1.00 | 0.402 | |||
Serum albumin (g/L) | 0.74 | 0.54–1.03 | 0.082 | 0.74 | 0.54–1.01 | 0.064 |
CRP (>20-fold x ULN) | 0.88 | 0.61–1.26 | 0.494 | |||
LDH (>2-fold x ULN) | 1.45 | 0.95–2.20 | 0.079 | 1.55 | 1.05–2.30 | 0.027 |
Lymphocyte count (mm3) | 1.00 | 1.00–1.00 | 0.708 | |||
Thrombocyte count (mm3) | 0.99 | 0.99–1.00 | 0.047 | 0.99 | 0.99–1.00 | 0.052 |
AKI stage 1 (ref) | ||||||
AKI stage 2 | 1.85 | 1.15–2.98 | 0.011 | 1.98 | 1.25–3.14 | 0.003 |
AKI stage 3 | 2.19 | 1.40–3.43 | <0.001 | 2.25 | 1.44–3.51 | <0.001 |
CRP, C-reactive protein; LDH, lactate dehydrogenase.