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. 2021 Feb 22;12(8):1490–1500. doi: 10.1111/jdi.13493

Table 1.

The qRT‐PCR test of circulating exosomes isolated from plasma in GDM and NGT groups

NGT (N = 61) GDM (N=57) t/t'/z/F P
x¯±s
M¯±Q
x¯±s
M¯±Q
OGTT 0 h (mmol/L) 4.45 ± 0.39 4.43 ± 0.62 5.20 ± 0.85 5.20 ± 0.91 5.236 <0.001
OGTT 1 h (mmol/L) 6.75 ± 31.60 6.67 ± 2.47 11.14 ± 1.40 10.96 ± 1.58 13.857 <0.001
OGTT 2 h (mmol/L) 5.77 ± 1.10 5.80 ± 1.79 9.19 ± 1.74 8.98 ± 2.04 7.246 <0.001
HbA1C (%) 5.09 ± 0.35 5.00 ± 0.50 5.66 ± 0.51 5.50 ± 0.50 5.616 <0.001
Age (year) 30.00 ± 5.63 29.50 ± 7.00 32.30 ± 4.21 32.00 ± 6.00 2.213 0.030
Gestational weeks at delivery (days) 276.11 ± 8.14 278.00 ± 14.00 273.46 ± 9.69 274.00 ± 15.00 1.118 0.264
Gravidity 2.31 ± 1.25 2.00 ± 2.00 2.44 ± 1.04 2.00 ± 1.00 0.676 0.499
Parity 1.46 ± 0.61 1.00 ± 1.00 1.77 ± 0.58 2.00 ± 1.00 2.502 0.012
weight§ (kg) 58.71 ± 11.21 55.00 ± 15.00 65.54 ± 11.15 65.00 ± 14.50 3.098 0.002
Weight (kg) 75.12 ± 13.47 71.00 ± 17.50 80.39 ± 11.85 78.70 ± 13.70 2.424 0.123
Increase of weight during pregnancy (kg) 16.41 ± 4.73 16.00 ± 7.00 14.86 ± 5.06 15.00 ± 4.50 2.424 0.123
BMI§ 22.32 ± 3.80 21.49 ± 5.90 25.10 ± 4.10 24.42 ± 4.90 3.385 0.001
BMI 28.59 ± 4.67 27.34 ± 5.60 30.81 ± 4.43 30.26 ± 4.75 2.168 0.145
Increase of BMI during pregnancy 6.26 ± 1.82 5.88 ± 2.78 5.71 ± 1.95 5.58 ± 1.84 2.168 0.145
Systolic blood pressure (mmHg) 125.14 ± 9.03 126.00 ± 11.00 129.83 ± 17.30 127.50 ± 18.00 1.235 0.217
Diastolic blood pressure (mmHg) 77.34 ± 5.60 78.00 ± 7.00 83.37 ± 10.89 83.00 ± 11.50 3.378 0.001
White blood cell count (×109/l) 9.45 ± 2.31 8.66 ± 3.90 8.74 ± 1.81 8.80 ± 2.49 0.931 0.352
Percentage of Neutrophil (%) 72.26 ± 6.83 71.80 ± 7.80 73.94 ± 6.57 74.43 ± 7.70 1.153 0.252
Percentage of lymphocyte (%) 20.56 ± 5.24 20.40 ± 7.10 19.14 ± 5.89 19.00 ± 8.60 1.151 0.253
Neutrophil‐lymphocyte ratio 4.34 ± 4.47 3.46 ± 1.55 4.48 ± 2.26 3.98 ± 2.10 1.294 0.196
Hemoglobin (g/l) 115.40 ± 11.95 117.00 ± 20.00 114.08 ± 14.86 111.00 ± 20.00 0.439 0.661
Platelets count (×109/l) 241.86 ± 55.44 250.00 ± 77.00 212.40 ± 57.47 208.00 ± 87.50 2.377 0.020
Abdominal circumference (cm) 103.86 ± 8.52 102.00 ± 8.00 107.75 ± 7.72 106.00 ± 9.50 0.390 0.534
Weight of the new born baby (g) 3418.57 ± 432.29 3390.00 ± 660.00 3666.15 ± 610.39 3600.00 ± 785.00 2.073 0.041
MiRNA‐125b 2.36 ± 1.48 2.06 ± 2.31 0.63 ± 1.34 0.60 ± 1.91 38.962 <0.001
MiRNA‐144 0.71 ± 2.45 0.92 ± 3.20 2.84 ± 2.89 3.14 ± 4.39 15.909 <0.001

BMI, body mass index; GDM, gestational diabetes mellitus; HbA1c, glycated hemoglobin; MiRNA, microribonucleic acid; NGT, normal glucose tolerance; OGTT, oral glucose tolerance test.

Within one standard deviation of the mean.

Within one quarter of the median.

§

Before pregnancy.

Before delivery.