Figure 7.

EPM results. A, Number of times spent immobile. B, Duration of time spent immobile. C, Number of entries into open arms. D, Time spent in open arms. E, Number of entries into closed arms. F, Time spent in closed arms. The F test was used for data analysis. Treatment, sex, and treatment by sex interaction were included in the model. Treatment effects were analyzed with dam nested under treatment and used as error term. There was significant (p = 0.01) treatment effect on number of times (A) and duration of time (B) spent immobile. Error bars represent SEM. Number of replicates tested = 13 female and 13 male mice for CTL group, 10 female and 10 male mice for OXY group.