Table 4.

In silico ADME properties of selected compounds.

N°	Name	Bbb	Buffer_Solubility _mg_l	CYP450_2c19 Inhibition	CYP450_2c9 Inhibition	CYP_2d6 Inhibition	CYP_2d6 Substrate	CYP450_3a4 Inhibition	CYP450_3a4 Substrate	HIA %	Pgp Inhibition	Sklogd	Sklogp_
1	Gallic acid	0.348	1.56e006	Yes	Yes	No	No	Yes	No	53.696	No	0.132	1.380
2	Methyl gallate	0.379	136319	No	Yes	No	No	Yes	No	69.746	No	1.414	1.414
6	Protocatechuic acid	0.059	3358.28	No	No	No	Weakly	No	Substrate	88.561	No	−1.39	0.012
7	Hinokiflavone	0.116	0.197	Yes	Yes	No	No	Yes	Weakly	86.954	Yes	4.726	4.726
11	Kaempferol	0.286	22.077	Yes	Yes	No	No	Yes	No	79.439	No	1.62	1.620
12	Myricetin	0.110	520.444	Yes	Yes	No	No	Yes	Weakly	40.964	No	1.72	1.726
13	Butein	0.425	276.948	Yes	Yes	No	No	Yes	No	80.604	No	2.838	2.838
14	β-caryophyllene	13.319	5.322	Yes	Yes	No	No	No	Substrate	100	Yes	4.896	4.896
15	Artemisinin	1.305	565.609	No	Yes	No	No	Yes	Substrate	96.314	No	1.6861	1.686
16	Camphor	0.867	20539.8	No	Yes	No	No	Yes	Substrate	100	Yes	2.085	2.085