Table 2.
Trial outcomes of patients randomised to convalescent plasma (CCP) compared with standard of care (SOC)
| Outcome | Overall | CCP | SOC | RR* | P value |
| Primary outcome | |||||
| Time to two consecutively negative reverse transcriptase-PCR, median (IQR), days | n=136 | n=69 | n=67 | ||
| 5.5 (4–8) | 6 (4–11) | 4 (4–6) | 0.196 | ||
| Secondary outcomes | |||||
| Time to symptom resolution among symptomatic patients, median (IQR) | n=120 | n=59 | n=61 | ||
| 2 (1–4) | 2 (1–4) | 2 (1–4) | 0.772 | ||
| Progression to severe/critical disease (oxygen saturation <93% or needing oxygen) | n=70 | n=41 | n=29 | ||
| 16 (22.9) | 9 (22.0) | 7 (24.1) | 0.91 (0.38 to 2.16) | 0.830 | |
| Mortality | n=136 | n=69 | n=67 | ||
| 18 (13.2) | 10 (14.5) | 8 (11.9) | 0.661 | ||
*Unadjusted risk ratio.