Figure 5.

Effect of rhu-pGSN on MPs from control and decompressed mice. Blood was obtained from control or decompressed male mice and centrifuged as described in methods. MPs suspensions were divided and where shown at time 0, 200 µg/mL rhu-pGSN was added. At 30-min intervals, samples were fixed. The number of remaining MPs and the percentage of particles that bound fluorescent phalloidin were quantified. Data are expressed as means ± SE, n = 5 for each sample, *indicates significantly different from the value at time 0, P < 0.05, RM-ANOVA. MP, microparticles; rhu-pGSN, recombinant human-plasma gelsolin; RM, repeated-measures; pGSN, plasma gelsolin.