Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 11;46:116364. doi: 10.1016/j.bmc.2021.116364

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Elsevier Ltd. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Scheme 3 — Reagents and conditions: a) cyclopropyl magnesium bromide, THF, 0 °C to rt, 37% of 18; b) isopropenyl magnesium bromide, THF, 0 °C to rt, 68% of 20; c) methanesulfonic acid, CH₂Cl₂, 50% of 19, 45% of 21; d) Pd/C, H₂, HCOOH/CH₃OH, 47% of 2d; e) BCl₃, CH₂Cl₂, −30 °C, 14% of 2e; f) NH₂OH.HCl, H₂O, 40 °C, 71%.