Table 2.

Methadone and EDDP in sweat patches

	Patch 1 (ng/patch)		Patch 2 (ng/patch)		Patch 3 (ng/patch)		Patch 4 (ng/patch)		Patch 5 (ng/patch)
Individual no	Methadone	EDDP	Methadone	EDDP	Methadone	EDDP	Methadone	EDDP	Methadone	EDDP
1	523	4.5	961	7.5	1314**	11	299	5.4	2116**	15
2	193	2.9	238	3.2	724	5.3	824	6.5	976	6.6
3	30	1.9*	72	2.1*	62	2.1*	92	2.3*	223	2.7
4	205	2.7	348	3.3	825	5.8	574	4.4	676	4.8
5	131	2.3*	170	2.8	400	3.4	342	3.3	302	3.3
6	187	2.5	294	2.8	438	3.6	468	3.7	362	3.4
7	727	6.7	2005**	15	4780**	31	3676**	20	4593**	26
8	34	2.2*	135	3.2	245	4.0	348	5.1	822	9.5
9	147	2.2*	526	3.6	868	4.7	919	4.7	1102**	4.8
10	1622**	5.8	2541**	7.1	1213**	4.9	4021**	10	4389**	10
11	339	3.2	550	4.3	706	4.9	1221**	6.5	1321**	5.7
12	211	3.1	898	8.1	1759**	13	1383**	9.6	1466**	9.5
13	562	4.6	874	6.5	1424**	10	1927**	13	2356**	14
14	542	3.4	896	4.8	1231**	5.9	1351**	5.8	1705**	6.7
15	19	1.8*	31	1.9*	47	1.9*	116	2.1*	88	2.0*

^*Value below LOQ (5.0 ng/patch for methadone and 2.5 ng/patch for EDDP) and above LOD (2.5 ng/patch for methadone and 1.5 ng/patch for EDDP)

^**Approximated value, concentration above the highest calibration point (1000 ng/patch for methadone and 500 ng/patch for EDDP)