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. 2021 May 28;28(5):1062–1071. doi: 10.1007/s12282-021-01241-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Wnt5a expression diminishes the sensitivity to tamoxifen, paclitaxel, and cyclophosphamide. MCF-7, MCF-7/Wnt5a (+), and MCF-7/Wnt5a (−) cells were exposed to 15 µM tamoxifen (a), 200 nM paclitaxel (b), 8000 µM cyclophosphamide (c), 800 nM epirubicin (d), or 400 µM 5-fluorouracil (e). Results are represented as the mean ± S.D. of 6 measurements. *P < 0.001; **P = 0.021 (Welch’s t-test); n.s. not significant