Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Overview of PPARα activation and regulation. PPARα activity is mediated by intra/extra-cellular metabolic signaling. Fasting induces elevation of fatty acids, the insulin signaling pathway, elevation of blood glucose, and glucagon which may stimulate expression and/or activity of PPARα under physiological metabolic conditions leading to increased lipid consumption.
