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. Author manuscript; available in PMC: 2022 Aug 26.
Published in final edited form as: J Biomech. 2021 Jun 17;125:110580. doi: 10.1016/j.jbiomech.2021.110580

Figure 7: Osteogenic gene expression and mineral deposition under free-swelling (FS) or 10% dynamic compression (DC) conditions.

Figure 7:

Samples were analyzed immediately after the final loading cycle in each group for mRNA expression of RUNX2 (A), osteopontin (OPN) (B), Yes-associated protein (YAP) (C), and the YAP-TEAD transcriptional target gene, Cysteine-rich angiogenic inducer 61 (CYR61) (D), calculated as fold change over free-swelling controls, normalized to GAPDH. Data are shown as mean ± s.d. with individual data points. ANOVA with Tukey’s post-hoc tests were used to determine significance (* p < 0.05, ** p < 0.01). Mineral deposition was evaluated by alizarin red staining on histological sections (E) (scale bar = 100 μm). N = 4 per group.