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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Jun 24;226:108843. doi: 10.1016/j.drugalcdep.2021.108843

Figure 1:

Figure 1:

Psychotropic-drug-implicated age-adjusted death rate per 100,000 (lines) and number of deaths (table) by year, total and by type

Note: Psychotropic-drug-implicated deaths are defined as those with multiple cause of death ICD-10 codes T40, T42, and T43, but not an underlying. cause of death of drug poisoning (X40-X44, X60-X64, X85, and Y10-Y14). For underlying cause of death ICD-12 codes defined as medical and external, see Appendix B.

Note: For the total death rate, there is a significant increasing trend (p<.05) across all years 1999-2019 with a best-fitting model of 2 joinpoints and 3 slopes (1999-2003, 2003-2013, 2013-2019). For the medical death rate, there is a significant increasing trend (p<.05) from 1999-2003 and 2014-2019 with a best-fitting model of 2 joinpoints and 3 slopes. For the external death rate, there is a significant increasing trend (p<.05) across all years 1999-2019 with a best-fitting model of 1 joinpoint and 2 slopes (1999-2014, 2014-2019).