Table 2:

Psychotropic-drug-induced deaths relative to all deaths within ICD-10 multiple cause of death categories for select psychotropic drugs

	All years 1999-2019		1999		2019
	All deaths	Psychotropic-drug-implicated are about 1 in X deaths	All deaths	Psychotropic-drug-implicated are about 1 in X deaths	All deaths	Psychotropic-drug-implicated are about 1 in X deaths
Cocaine	157,928	10	4,494	8	16,912	16
Psychostimulants	94,161	7	700	5	18,386	8
Benzodiazepines	124,439	24	1,219	16	10,111	25
Cannabis	7,268	4	49	4	1,101	4
Opioids	515,285	29	8,647	24	51,178	39
Heroin	132,347	67	2,103	75	14,233	67
Natural and semi-synthetic	195,986	22	2,915	23	12,487	21
Methadone	75,968	27	831	21	2,893	19
Synthetic other than methadone	164,154	51	772	20	36,883	70

Note: “All deaths” column includes all deaths where substance was listed as a multiple cause of death regardless of underlying cause. As noted by the CDC, the percentage of drug overdose deaths that identified the specific drugs involved varied by year, ranging from 75%-79% from 1999 through 2013 and increasing from 81% in 2014 to 94% in 2019 (Hedegaard, et al., 2020). See Appendix C for additional information on unidentified substances.