Table 2.
Characteristics of PLCO Trial Participants in the Incident and Recurrent Adenoma Analyses by Case and Control Status
| Characteristic | Incident adenoma |
Recurrent adenoma |
||
|---|---|---|---|---|
| Cases (n= 1221) |
Controls (n= 19,626) |
Cases (n= 862) |
Controls (n= 877) |
|
| Age in years, mean (IQR) | 62.4 (8.6) | 62.7 (8.3) | 63.3 (7.7) | 63.1 (8.4) |
| Male, n (%) | 806 (66.0) | 10,699 (54.5) | 614 (71.2) | 499 (56.9) |
| White, n (%) | 1,095 (89.7) | 17,187 (87.6) | 786 (91.2) | 836 (95.3) |
| Family history of colorectal cancer, n (%) | 125 (10.2) | 1,691 (8.6) | 106 (12.3) | 105 (12.0) |
| Body mass index in kg/m2, mean (IQR) | 27.6 (5.7) | 27.1 (5.4) | 27.9 (5.6) | 27.4 (5.6) |
| Physical activity >3 hours/week, n (%) | 261 (21.4) | 4,587 (23.4) | 192 (22.3) | 192 (21.9) |
| Cigarette smoking, n (%) | ||||
| Current | 136 (11.1) | 1,053 (5.4) | 129 (15.0) | 125 (14.3) |
| Former | 566 (46.4) | 8,076 (41.1) | 437 (50.7) | 415 (47.3) |
| History of, n (%) | ||||
| Cardiovascular diseases1 | 440 (36.0) | 6,859 (34.9) | 314 (36.4) | 310 (35.3) |
| Arthritis | 363 (29.7) | 6,630 (33.8) | 265 (30.7) | 298 (34.0) |
| Osteoporosis | 30 (2.5) | 742 (3.8) | 20 (2.3) | 22 (2.5) |
| Diabetes mellitus | 88 (7.2) | 1,204 (6.1) | 59 (6.8) | 68 (7.8) |
1
Coronary artery disease, heart attack, hypertension, stroke