Table 1.
Characteristics of the study populations.
| Characteristics | Discovery set | Characteristics | Prospective set | ||
|---|---|---|---|---|---|
| CRC Cases (n = 20) | Controls (n = 20) | CRC Cases (n = 198) | Controls (n = 178) | ||
| Age at sampling | Age at sampling | ||||
| Mean (SD) | 64.6 (5.9) | 62.2 (6.6) | |||
| Mean (SD) | 64.8 (12.3) | 64.7 (12.1) | Median (range) | 65 (50–75) | 62 (50–75) |
| Age at diagnosis | |||||
| Median (range) | 64 (47–88) | 64 (47–87) | Mean (SD) | 71.3 (6.8) | – |
| Median (range) | 71.3 (53–86) | – | |||
| Gender– counts (%) | Gender– counts (%) | ||||
| Male | 11 (55.0) | 11 (55.0) | Male | 122 (61.6) | 89 (50.0) |
| Female | 9 (45.0) | 9 (45.0) | Female | 76 (38.4) | 89 (50.0) |
| TNM stage– counts (%) | TNM stage at diagnosis– counts (%) | ||||
| Stage 0 | 1 (5.0) | – | Stage 0 | 14 (7.1) | – |
| Stage I | 1 (5.0) | – | Stage I | 20 (10.1) | – |
| Stage II | 9 (45.0) | – | Stage II | 61 (30.8) | – |
| Stage III | 4 (20.0) | – | Stage III | 30 (15.2) | – |
| Stage IV | 4 (20.0) | – | Stage IV | 28 (14.1) | – |
| Unknown | 1 (5.0) | – | Unknown | 45 (22.7) | – |
CRC colorectal cancer, n number, SD standard deviation, TNM Tumor Nodes Metastasis classification.