Table 4.

Associations between exposure to the John F. Kennedy assassination and placental abnormalities among participants from the Boston study site (n = 6959)

	Prevalence	Unadjusted		Adjusteda
	N (%)	OR	95% CI	OR	95% CI
Maternal acute inflammation	976 (14.0)
Unexposed		Reference
First trimester		0.95	0.72, 1.27	0.95	0.72, 1.26
Second trimester		0.82	0.61, 1.10	0.83	0.62, 1.11
Third trimester		1.27	0.94, 1.71	1.28	0.95, 1.73
Fetal acute inflammation	1665 (23.9)
Unexposed		Reference
First trimester		0.61	0.47, 0.79	0.61	0.47, 0.80
Second trimester		0.79	0.63, 1.00	0.80	0.63, 1.01
Third trimester		1.34	1.05, 1.71	1.34	1.05, 1.71
Maternal vascular malperfusion	1398 (20.1)
Unexposed		Reference
First trimester		0.66	0.50, 0.86	0.65	0.50, 0.86
Second trimester		0.83	0.65, 1.06	0.82	0.64, 1.05
Third trimester		1.26	0.97, 1.64	1.27	0.98, 1.65
Fetal vascular malperfusion	68 (1.0)
Unexposed		Reference
First trimesterb
Second trimester		0.64	0.20, 2.05	0.66	0.20, 2.15
Third trimester		1.88	0.80, 4.40	1.82	0.77, 4.30

CI confidence interval, OR odds ratio

^aModels adjusted for maternal age, race, gestational age, fetal sex, and smoking status

^bNo exposed placentas with fetal vascular malperfusion in the first trimester