Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 10;12:4817. doi: 10.1038/s41467-021-25087-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — Structures of BG505 SOSIP antigens in complex with polyclonal antibodies targeting gp120–gp120 interface (A, B) and base epitopes (C). BG505 SOSIP trimers are shown in gray with N-linked glycans in golden yellow. Antibodies are colored using the same scheme as in Figs. 1 and 2. Inferred heavy and light chains for each antibody are represented in different colors and labeled in each panel (HC and LC, respectively). The most relevant epitope/paratope components are indicated in the panels. Surface representation is used for the full immune complex (left side of each panel). Trimer residues in direct contact with the antibodies are colored blue (ribbon and stick representation). Engineered stabilizing residues are represented as sticks and colored orange. EM Map is displayed as transparent light gray surfaces in panels (A) and (B).