FIGURE 1.

Identification of APPswe-overexpressing cell line. Five stable cell lines were obtained by viral infection and screening, four of which were infected by lentivirus containing the APPswe gene. The other cell line was infected with an empty vector. The expression levels of APP were determined by (A) real-time PCR (compared with the normal group, ^* p < 0.05, ^** p < 0.01, n = 3) and (B) western blot (compared with the normal group, ^* p < 0.05, n = 4). (C) The levels of Aβ_1-42 were measured by ELISA (compared with the normal group, ^** p < 0.01, n = 6).