Table 2.

Comparison of baseline and 1-year follow-up data for patients with mild cognitive impairment (MCI), Alzheimer's disease (AD) and probable dementia with Lewy bodies (DLB).

	MCI ( n = 50)				AD ( n = 105)				DLB ( n = 22)
	Baseline	1 year later	Change	P	Baseline	1year later	Change	P	Baseline	1year later	Change	P
Physical activity	4.0 ± 3.4	1.7 ± 2.1	1.5 ± 2.9	<0.001***	3.2 ± 3.1	1.7 ± 2.1	1.5 ± 2.2	<0.001***	2.5 ± 3.7	1.1 ± 2.0	1.4 ± 2.2	0.006**
Social contact	7.2 ± 2.8	6.4 ± 3.3	0.9 ± 2.4	0.014*	5.7 ± 3.6	4.3 ± 3.5	1.3 ± 3.2	<0.001***	4.9 ± 3.4	3.0 ± 3.4	1.9 ± 2.5	0.003**
MMSE	24.5 ± 4.8	24.0 ± 5.8	0.4 ± 3.6	0.298	13.0 ± 7.0	11.4 ± 7.4	1.6 ± 3.4	<0.001***	13.7 ± 7.0	10 ± 6.9	3.6 ± 5.5 c	0.002**
MOCA	20.4 ± 4.4	20.1 ± 5.5	0.2 ± 3.4	0.560	8.8 ± 5.7	7.8 ± 5.9	1.0 ± 3.2 a	0.001**	9.9 ± 5.9	7.3 ± 5.4	2.5 ± 5.0 c	0.007**
NPI	2.7 ± 5.0	2.8 ± 5.2	0.1 ± 2.6	0.710	9.7 ± 11.2	12.2 ± 13.5	2.7 ± 8.2	0.008**	18.6 ± 14.4	20.9 ± 14.8	2.5 ± 10.4	0.139
ADL	20.7 ± 1.1	21.3 ± 2.4	0.6 ± 2.2	0.127	34.7 ± 14.3	41.1 ± 17.8	6.4 ± 9.8 b	<0.001***	36.1 ± 14.8	44.7 ± 20.3	8.6 ± 12.2 c	0.002**
HAMD	2.2 ± 3.9	2.9 ± 5.3	0.7 ± 4.4	0.726	4.2 ± 4.4	4.9 ± 5.1	0.8 ± 2.6	0.002**	9.3 ± 8.0	9.2 ± 6.9	−0.1 ± 5.9	0.665
ESS	1.0 ± 1.7	1.3 ± 2.4	0.2 ± 1.1	0.107	2.6 ± 4.0	3.4 ± 5.1	0.8 ± 2.2	<0.001***	5.5 ± 4.8	6.4 ± 6.4	1.3 ± 3.7	0.201

Baseline mean compared with 1-year follow-up, *P < 0.05, **P < 0.01, ***P < 0.001.

Changes of the evaluated scores compared between MCI and AD, ^aP < 0.05, ^bP < 0.001; changes of the evaluated scores compared between MCI and DLB, ^cP < 0.01. MMSE, mini mental status exam; MOCA, Montreal cognitive assessment; NPI neuropsychiatric inventory; ADL, activities of daily living; HAMD, Hamilton depression scale; ESS, Epworth sleepiness scale.