Table 3.

Correlation between cognitive and neuropsychiatric decline and hypothesized related factors in Alzheimer's disease (AD) and probable dementia with Lewy bodies (DLB).

	AD				DLB
	MMSE worse		NPI worse		MMSE worse		NPI worse
	r	P	r	P	r	P	r	P
Age (baseline)	−0.030	0.760	0.077	0.434	0.147	0.514	0.141	0.531
Gender	0.001	0.992	0.061	0.535	−0.101	0.654	0.044	0.846
Disease duration (baseline)	−0.09	0.924	−0.043	0.664	−0.383	0.079	−0.149	0.507
Marital status (baseline)	0.170	0.083	0.034	0.729	−0.232	0.299	−0.251	0.260
Education level	0.053	0.592	−0.134	0.172	0.205	−0.359	0.350	0.110
Physical activity (change)	0.274	0.005**	0.040	0.685	−0.142	0.527	0.299	0.177
Social contact (change)	0.069	0.485	0.273	0.005**	0.136	0.547	0.496	0.029*
Sleep disturbance (baseline)	0.208	0.033*	0.279	0.004**	0.210	0.349	0.001	1.000
MMSE (baseline)	0.002	0.987	−0.274	0.005**	0.382	0.080	0.182	0.417
NPI (baseline)	0.137	0.163	−0.090	0.359	−0.120	0.594	−0.333	0.131
HAMD (baseline)	0.125	0.203	0.175	0.075	−0.032	0.889	−0.341	0.121
ESS (baseline)	0.124	0.209	0.298	0.002**	−0.014	0.953	0.058	0.804

*P < 0.05, **P < 0.01; MMSE, mini-mental status exam; NPI neuropsychiatric inventory; HAMD, Hamilton depression scale; ESS, Epworth sleepiness scale.