Table 4.
Multiple linear regression analysis of cognitive and neuropsychiatry changes in Alzheimer's Disease.
| MMSE | NPI | |||
|---|---|---|---|---|
| Beta (SD) | P | Beta (SD) | P | |
| Age | −0.065 | 0.511 | 0.042 | 0.655 |
| Gender | −0.016 | 0.872 | 0.130 | 0.161 |
| Disease duration | −0.002 | 0.986 | −0.014 | 0.880 |
| Physical activity (change) | 0.307 | 0.003** | 0.049 | 0.609 |
| Social contact (change) | −0.131 | 0.219 | 0.204 | 0.045* |
| Sleep disturbance | 0.157 | 0.127 | 0.228 | 0.021* |
| MMSE (baseline) | 0.141 | 0.177 | −0.137 | 0.168 |
| NPI (baseline) | 0.131 | 0.297 | −0.194 | 0.105 |
| HAMD (baseline) | 0.115 | 0.410 | 0.051 | 0.697 |
| ESS (baseline) | 0.085 | 0.427 | 0.253 | 0.014* |
| Adjusted R2 | 0.101 | 0.193 | ||
| P-value of F | 0.027* | 0.001** | ||
*P < 0.05, **P < 0.01; MMSE, mini-mental status exam; NPI, neuropsychiatric inventory; HAMD, Hamilton depression scale; ESS, Epworth sleepiness scale.