TABLE 3.
Gene Ontology analysis of the top ten hyper-methylated mRNAs.
| GO.ID | Term | Ontology | Count | p-value | Fdr | Enrichment score |
|---|---|---|---|---|---|---|
| GO:0000902 | Cell morphogenesis | Biological process | 7 | 7.0344E-05 | 0.324473551 | 4.152772946 |
| GO:0032989 | Cellular component morphogenesis | Biological process | 7 | 0.000128477 | 0.324473551 | 3.891174337 |
| GO:0022604 | Regulation of cell morphogenesis | Biological process | 5 | 0.000166488 | 0.324473551 | 3.778618248 |
| GO:0006928 | Movement of cell or subcellular component | Biological process | 8 | 0.000393 | 0.324473551 | 3.405607496 |
| GO:2000463 | Positive regulation of excitatory postsynaptic potential | Biological process | 2 | 0.000525054 | 0.324473551 | 3.279795677 |
| GO:0120,039 | Plasma membrane bounded cell projection morphogenesis | Biological process | 5 | 0.00058802 | 0.324473551 | 3.230607569 |
| GO:0048858 | Cell projection morphogenesis | Biological process | 5 | 0.000599981 | 0.324473551 | 3.22186279 |
| GO:0031175 | Neuron projection development | Biological process | 6 | 0.000627138 | 0.324473551 | 3.202636833 |
| GO:0019221 | Cytokine-mediated signaling pathway | Biological process | 4 | 0.000657648 | 0.324473551 | 3.18200643 |
| GO:0045785 | Positive regulation of cell adhesion | Biological process | 4 | 0.00067698 | 0.324473551 | 3.169424277 |
| GO:0120,025 | Plasma membrane bounded cell projection | Cellular component | 8 | 0.000840205 | 0.232167614 | 3.075614779 |
| GO:0042995 | Cell projection | Cellular component | 8 | 0.000972547 | 0.232167614 | 3.012089301 |
| GO:0043197 | Dendritic spine | Cellular component | 3 | 0.001088661 | 0.232167614 | 2.963107415 |
| GO:0044309 | Neuron spine | Cellular component | 3 | 0.001120031 | 0.232167614 | 2.950770139 |
| GO:0044456 | Synapse part | Cellular component | 5 | 0.001379925 | 0.232167614 | 2.860144529 |
| GO:0098794 | Postsynapse | Cellular component | 4 | 0.001689647 | 0.232167614 | 2.772204087 |
| GO:0014069 | Postsynaptic density | Cellular component | 3 | 0.002740157 | 0.232167614 | 2.562224576 |
| GO:0099572 | Postsynaptic specialization | Cellular component | 3 | 0.002796098 | 0.232167614 | 2.55344754 |
| GO:0032279 | Asymmetric synapse | Cellular component | 3 | 0.002881334 | 0.232167614 | 2.540406329 |
| GO:0045202 | Synapse | Cellular component | 5 | 0.002960384 | 0.232167614 | 2.528652018 |
| GO:0051219 | Phosphoprotein binding | Molecular function | 2 | 0.005431961 | 1 | 2.265043371 |
| GO:0017124 | SH3 domain binding | Molecular function | 2 | 0.006663867 | 1 | 2.176273674 |
| GO:0030594 | Neurotransmitter receptor activity | Molecular function | 2 | 0.007384559 | 1 | 2.131675429 |
| GO:0048406 | Nerve growth factor binding | Molecular function | 1 | 0.011176355 | 1 | 1.951699809 |
| GO:0001591 | Dopamine neurotransmitter receptor activity, coupled via Gi/Go | Molecular function | 1 | 0.012287459 | 1 | 1.910537933 |
| GO:0015250 | Water channel activity | Molecular function | 1 | 0.014506118 | 1 | 1.838448788 |
| GO:0004952 | Dopamine neurotransmitter receptor activity | Molecular function | 1 | 0.015613677 | 1 | 1.806494817 |
| GO:0005372 | Water transmembrane transporter activity | Molecular function | 1 | 0.015613677 | 1 | 1.806494817 |
| GO:0043121 | Neurotrophin binding | Molecular function | 1 | 0.015613677 | 1 | 1.806494817 |
| GO:0035240 | Dopamine binding | Molecular function | 1 | 0.02003213 | 1 | 1.698272881 |