TABLE 4.

Gene Ontology analysis of the top ten hypo-methylated mRNAs.

GO.ID	Term	Ontology	Count	p-value	Fdr	Enrichment score
GO:0019221	Cytokine-mediated signaling pathway	Biological process	6	3.15545E-05	0.16723586	4.500939235
GO:0045071	Negative regulation of viral genome replication	Biological process	3	8.13812E-05	0.16723586	4.089475756
GO:0051707	Response to other organism	Biological process	8	0.000110304	0.16723586	3.957409854
GO:0043207	Response to external biotic stimulus	Biological process	8	0.000113542	0.16723586	3.944843243
GO:0009607	Response to biotic stimulus	Biological process	8	0.000146422	0.16723586	3.834392194
GO:0006955	Immune response	Biological process	9	0.000147975	0.16723586	3.829813087
GO:1903901	Negative regulation of viral life cycle	Biological process	3	0.000272286	0.263767544	3.564974349
GO:0045069	Regulation of viral genome replication	Biological process	3	0.000350815	0.297359886	3.454921375
GO:0048525	Negative regulation of viral process	Biological process	3	0.000516858	0.389424083	3.286628429
GO:0019079	Viral genome replication	Biological process	3	0.000615908	0.39115453	3.210484097
GO:0000782	Telomere cap complex	Cellular component	1	0.019429856	1	1.711530414
GO:0000783	Nuclear telomere cap complex	Cellular component	1	0.019429856	1	1.711530414
GO:0005883	Neurofilament	Cellular component	1	0.021177942	1	1.674116247
GO:0005576	Extracellular region	Cellular component	8	0.021620359	1	1.665137091
GO:0034709	Methylosome	Cellular component	1	0.022923006	1	1.63972844
GO:0005687	U4 snRNP	Cellular component	1	0.024665052	1	1.607917962
GO:0034719	SMN-Sm protein complex	Cellular component	1	0.031603169	1	1.500269361
GO:0071004	U2-type prespliceosome	Cellular component	1	0.031603169	1	1.500269361
GO:0005615	Extracellular space	Cellular component	6	0.035593759	1	1.448626141
GO:0098802	Plasma membrane receptor complex	Cellular component	2	0.039506187	1	1.40333488
GO:0005125	Cytokine activity	Molecular function	4	0.000123343	0.1554123	3.908885157
GO:0005126	Cytokine receptor binding	Molecular function	4	0.000804967	0.507128913	3.094222177
GO:0008009	Chemokine activity	Molecular function	2	0.001352491	0.568046338	2.868865526
GO:0098772	Molecular function regulator	Molecular function	8	0.002030662	0.639658597	2.692362313
GO:0042379	Chemokine receptor binding	Molecular function	2	0.003183034	0.733701618	2.497158668
GO:0048018	Receptor ligand activity	Molecular function	4	0.003493817	0.733701618	2.456699818
GO:0030545	Receptor regulator activity	Molecular function	4	0.004505466	0.810983968	2.346260236
GO:0004791	Thioredoxin-disulfide reductase activity	Molecular function	1	0.016139095	1	1.792120819
GO:0070990	snRNP binding	Molecular function	1	0.016139095	1	1.792120819
GO:0004312	Fatty acid synthase activity	Molecular function	1	0.017593822	1	1.754639806