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. 2021 Jul 28;8:607886. doi: 10.3389/fmolb.2021.607886

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Copyright © 2021 Malik, Kumar, Ansari, Hemida, El Zowalaty, Abdel-Moneim, Ganesh, Salajegheh, Natesan, Sircar, Safdar, Vinodhkumar, Duarte, Patel, Klein, Rahimi and Dhama.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different strategies employed for the development of vaccines against SARS-CoV-2. Research institutions along with pharmaceutical companies across the world are adopting unique strategies to develop effective vaccines against SARS-CoV-2 and most of them target spike proteins and its functional domains. (A–D) The type of vaccine being developed includes subunit vaccine, mRNA vaccine, DNA vaccine and viral-vector based vaccines which aim to elicit humoral as well as cellular immune response against spike protein of SARS-CoV-2.