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. 2021 Jul 28;13:706544. doi: 10.3389/fnagi.2021.706544

Table 3.

Univariate and multivariate analyses for factors associated with recurrent stroke in comparison with the first-time stroke.

Parameters Univariate analysis Multivariate analysis
OR (95% CI) p -value OR (95% CI) p -value
Male 0.68 (0.32–1.46) 0.323
Age, year 1.01 (0.97–1.05) 0.517
BMI, kg/m2 0.10(0.87–1.15) 0.958
Hypertension 1.82 (0.74–4.51) 0.195
Dyslipidemia 0.55 (0.23–1.31) 0.174
Current smoking 1.35 (0.55–3.35) 0.512
Alcohol use 2.09 (0.68–6.41) 0.199
DM 1.13 (0.53–2.34) 0.761
CAD 4.47 (1.26–15.86) 0.020 4.61 (1.11–19.18) 0.035
Hs–CRP, mg/L 1.01 (0.96–1.11) 0.429
Culprit plaque stenosis, % a 1.25 (0.96–1.53) 0.101
Culprit plaque thickness, mm 1.00 (0.60–1.67) 0.996
Culprit plaque length, mm 1.02 (0.94–1.10) 0.652
Culprit plaque area, mm2 0.97 (0.92–1.02) 0.280
Culprit plaque burden, % a 2.03 (1.18–3.50) 0.011 2.44 (1.24–4.79) 0.010
Culprit plaque ER 2.51 (1.23–5.12) 0.011 2.50 (1.06–5.89) 0.036
Total plaque enhancement score 1.24 (1.04–1.48) 0.015 0.93 (0.72–1.19) 0.544
Total plaque number 1.47 (1.19–1.82) <0.001 1.54 (1.16–2.03) 0.003
a

OR based on every 10% increase.

BMI, body mass index; CAD, coronary artery disease; DM, diabetes mellitus; Hs-CRP, high-sensitivity C-reactive protein; ER, enhancement ratio.