Table 2.
The genotypic and allelic frequency of rs12537.
Groups | Allele frequency (%) | p-value | OR (95% CI) | p-hwe | ||
---|---|---|---|---|---|---|
T | C | |||||
Family history | Positive vs. Control | 0.175 | 0.205 | 0.1095 | 0.8226 (0.6475-1.045) | 0.6475 |
Negative vs. Control | 0.1774 | 0.205 | 1.44E-06 | 0.8362 (0.7775–0.8994) | 0.7775 | |
Positive vs. Negative | 0.175 | 0.1774 | 0.8945 | 0.9837 (0.7719–1.254) | 0.7719 | |
Menopausal status | Positive vs. Control | 0.1751 | 0.205 | 9.89E-05 | 0.8231 (0.7462–0.908) | 0.7462 |
Negative vs. Control | 0.1843 | 0.205 | 0.008677 | 0.8764 (0.7941–0.9672) | 0.7941 | |
Positive vs. Negative | 0.1751 | 0.1843 | 0.3245 | 0.9393 (0.8292–1.064) | 0.8292 | |
ER | Positive vs. Control | 0.1664 | 0.205 | 1.66E-08 | 0.7744 (0.7085–0.8464) | 0.7085 |
Negative vs. Control | 0.1938 | 0.205 | 0.2052 | 0.9321 (0.8360–1.0390) | 0.836 | |
Positive vs. Negative | 0.1664 | 0.1938 | 0.004006 | 0.8309 (0.7323–0.9427) | 0.7323 | |
PR | Positive vs. Control | 0.1678 | 0.205 | 6.13E-08 | 0.7822 (0.7155–0.8550) | 0.7155 |
Negative vs. Control | 0.1911 | 0.205 | 0.114 | 0.9163 (0.8222–1.021) | 0.8222 | |
Positive vs. Negative | 0.1678 | 0.1911 | 0.01379 | 0.8536 (0.7525–0.9683) | 0.7525 | |
HER-2 | Positive vs. Control | 0.1832 | 0.205 | 0.02393 | 0.8699 (0.7708–0.9818) | 0.7708 |
Negative vs. Control | 0.1728 | 0.205 | 1.14E-06 | 0.8101 (0.7441–0.8819) | 0.7441 | |
Positive vs. Negative | 0.1832 | 0.1728 | 0.2987 | 1.0740 (0.9388–1.2280) | 0.9388 |