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. 2021 Jul 28;12:710613. doi: 10.3389/fgene.2021.710613

FIGURE 2.

FIGURE 2

Circular Manhattan plot for associations of SNP with ewe composite traits at weaning by two GWAS approaches. The 4 circles, from outside to inside, represent Progeny Weaning Weight (PWW): pGWAS and eGWAS; Total Litter Weight at Weaning (TLWW): pGWAS and eGWAS; Litter Mean Weight at Weaning (LMWW): pGWAS and eGWAS. The outermost circle shows SNP density in a 1 Mb window for each chromosome. X-axis: SNP positions on chromosomes, Y-axis: –Log10 P-value. The red and blue dashed lines indicate the thresholds for genome-wide (1.22*10–5) and chromosome-wide (P < 1.67*10–4) statistical significance, respectively. The red and blue dots show associated and suggestive SNPs, respectively. pGWAS: GWAS using phenotypes as response variable; eGWAS: GWAS using EBVs as a response variable.