Table 7.

Skipping of Out-of-frame Exons for the Disruption of Gene Function.

Disease	Gene	Exon	Phase	Author, Year
Diabetes mellitus	MSTN	2	P	Eilers et al. 2021 (50)
DMD			P	Kemaladewi et al. 2011 (47)
Parkinson’s disease	LRRK2	41	P	Korecka et al. 2020 (48)
Prostate cancer	ERG	4	P	Li et al. 2020 (49)
Muscle fibrosis	ALK5	6	P	Kemaladewi et al. 2014 (51)
Familial hypercholesterolemia	APOB	27	P	Disterer et al. 2013 (52)

DMD: Duchenne muscular dystrophy; P: preclinical study