Table 5.

Effective PBM treatment: in vivo on tissues with higher number of mitochondria.

Authors	Wavelength (nm)	Fluence	Irradiance	Tissue type
Alves et al.25	808	$142.4\mathrm{J}/{\mathrm{cm}}^2$	$1.78{\mathrm{W}/\mathrm{cm}}^2$ 4 J, 50 mW, $0.028{\mathrm{cm}}^2$, 80 s per point	Arthritis
Oron et al.62,63	810	$0.3\mathrm{J}/{\mathrm{cm}}^2$	$5{\mathrm{mW}/\mathrm{cm}}^2$ 5 mW, area $1.1{\mathrm{cm}}^2$, 60 s	Heart
Oron et al.62,63	810	$0.9\mathrm{J}/{\mathrm{cm}}^2$	$5\mathrm{mW}/{\mathrm{cm}}^2$	Myocardium tissue
Castano et al.17	810	$30\mathrm{J}/{\mathrm{cm}}^2$	$50\mathrm{mW}/{\mathrm{cm}}^2$	Arthritis
Castano et al.17	810	$30\mathrm{J}/{\mathrm{cm}}^2$	$5\mathrm{mW}/{\mathrm{cm}}^2$	Arthritis
Castano et al.17	810	$3\mathrm{J}/{\mathrm{cm}}^2$	$5\mathrm{mW}/{\mathrm{cm}}^2$	Arthritis
Salehpour et al.59	810	$1.2\mathrm{J}/{\mathrm{cm}}^2$	$560{\mathrm{mW}/\mathrm{cm}}^2$ 39.3 W, spot size $0.07{\mathrm{cm}}^2$	Brain
Salehpour et al.64	810	$8\mathrm{J}/{\mathrm{cm}}^2$	$89{\mathrm{mW}/\mathrm{cm}}^2$ 6.2 W, spot size $0.07{\mathrm{cm}}^2$	Brain
Wu et al.78	810	$36\mathrm{J}/{\mathrm{cm}}^2$	$15{\mathrm{mW}/\mathrm{cm}}^2$	Brain
Blanco et al.70	1064	$250\mathrm{mW}/{\mathrm{cm}}^2$	$60{\mathrm{J}/\mathrm{cm}}^2$	Brain (human)
Disner et al.71	1064	$250\mathrm{mW}/{\mathrm{cm}}^2$	$60\mathrm{J}/{\mathrm{cm}}^2$	Brain (human)
Ando et al.13	810	$36\mathrm{J}/{\mathrm{cm}}^2$	$50\mathrm{mW}/{\mathrm{cm}}^2$	TBI
Zhang et al.67	810	Fluence reaching the cortex 1.8 to $2.5{\mathrm{J}/\mathrm{cm}}^2$ Average irradiance $36{\mathrm{J}/\mathrm{cm}}^2$	$150{\mathrm{mW}/\mathrm{cm}}^2$ Pulse freq 10 Hz, pulse duration 50 ms, 4 min	TBI
Salehpour et al.68	810	$1.2\mathrm{J}/{\mathrm{cm}}^2$	89 and $562{\mathrm{mW}/\mathrm{cm}}^2$ 35 and 240 mW 10 Hz, 50% duty cycle; $0.07{\mathrm{cm}}^2$	Brain
Baroni et al.68	Cluster with 69 LEDs 660/850 nm	$206.89\mathrm{J}/{\mathrm{cm}}^2$	$6.89{\mathrm{W}/\mathrm{cm}}^2$ 200 mW; 6 J per diode (30 s); $0.02{\mathrm{cm}}^2$ 30 J per application point $(5\times 6\mathrm{J})6$ application points: total energy 180 J	Femoral quadriceps
Zhang et al.80	635	$0.96\mathrm{J}/{\mathrm{cm}}^2$	$6.37{\mathrm{mW}/\mathrm{cm}}^2$ 5 mW, laser beam width 10 mm, 150 s	Preconditioning myocardium
Salehpour et al.59	660	$8\mathrm{J}/{\mathrm{cm}}^2$	$4.75{\mathrm{W}/\mathrm{cm}}^2$ 88% duty cycle, 200 mW, in contact three times a week, 7 mm diameter	Brain
Wu et al.78	660	$36\mathrm{J}/{\mathrm{cm}}^2$	$15{\mathrm{mW}/\mathrm{cm}}^2$	Brain
Lopes-Martins et al.18	655	$0.5\mathrm{J}/{\mathrm{cm}}^2$	$31.25{\mathrm{mW}/\mathrm{cm}}^2$ 2.5 mW, spot area $0.08{\mathrm{cm}}^2$, 25 mW, 32 s	Muscle
Lopes-Martins et al.18	655	$1\mathrm{J}/{\mathrm{cm}}^2$	$31.25{\mathrm{mW}/\mathrm{cm}}^2$ 2.5 mW, spot area $0.08{\mathrm{cm}}^2$, 25 mW, 80 s, 2.5 mW	Muscle