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. 2020 Dec 15;70(9):1734–1745. doi: 10.1136/gutjnl-2020-321190

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Profiling of reporter virus neutralisation by polyclonal immunoglobulins (pIg) from 104 patients infected by GT1 to GT6 viruses. (A) Distribution of HCV genotypes of chronically infected patients in the cohort. (B) Heatmap of pIg neutralisation data with efficient virus neutralisation in red and inefficient neutralisation in blue. Crossed white rectangle, data not available. (C) Rank-ordered representation of cell culture-derived HCV (HCVcc) viruses based on their susceptibility to patient-derived pIg neutralisation. The silhouette of the violin is proportional to the number of sera with that neutralisation capacity, the solid blue bar covers 50% of all data, that is, second and third quartile, the grey dot in the middle indicates the median and ‘+’ the mean.