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. 2020 Dec 15;70(9):1734–1745. doi: 10.1136/gutjnl-2020-321190

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Identification of elite neutralisers using six reference viruses. (A) Heatmap of virus neutralisation by 392 patient-derived polyclonal immunoglobulin (pIg) against given six reference viruses. (B) Confirmation that the 2% best patient-derived pIg samples efficiently neutralise 12 different cell culture-derived HCV (HCVcc) strains.