TABLE 3.
Variables associated with presence of insulin resistance after 7 years.
| OR | 95% IC | P value | ||
| Clinical characteristics | ||||
| Male gender | 1.29 | 0.81 | 2.05 | 0.28 |
| Age (years) | 1.02 | 0.77 | 1.35 | 0.92 |
| Weight (kg) | 1.04 | 1.02 | 1.06 | <0.0001 |
| Obesity (BMI ≥ 30 kg/m2) | 3.13 | 1.58 | 6.22 | <0.001 |
| Hip circumference (cm) | 1.03 | 1.003 | 1.06 | 0.003 |
| Waist circumference (cm) | 1.05 | 1.03 | 1.08 | <0.0001 |
| Epworth scale score (unit) | 1.06 | 0.99 | 1.13 | 0.09 |
| Antihypertensive (Yes) | 1.72 | 1.07 | 2.78 | 0.03 |
| Biological characteristics | ||||
| Prediabetes state (Yes/No) | 1.38 | 0.68 | 2.83 | 0.37 |
| Total cholesterol (g/L) | 0.62 | 0.33 | 1.17 | 0.14 |
| LDLc (g/L) | 0.57 | 0.27 | 1.21 | 0.14 |
| HDLc (g/L) | 0.66 | 0.36 | 1.24 | 0.2 |
| Triglycerides (g/L) | 1.83 | 1.3 | 2.56 | 0.0005 |
| CRP (mg/L) | 1.03 | 0.99 | 1.07 | 0.14 |
| Ambulatory blood pressure | ||||
| 24-h Systolic BP (mmHg) | 1.01 | 0.99 | 1.03 | 0.31 |
| 24-h Diastolic BP (mmHg) | 0.99 | 0.96 | 1.03 | 0.69 |
| DEXA | ||||
| Head fat mass* (%) | 1.07 | 0.91 | 1.26 | 0.4 |
| Trunk fat mass* (%) | 1.05 | 1.01 | 1.08 | 0.006 |
| Body fat mass* (%) | 1.03 | 1 | 1.06 | 0.05 |
| Respiratory polygraphy | ||||
| SpO2 mean (%) | 0.88 | 0.78 | 0.98 | 0.03 |
| SpO2 min (%) | 1.23 | 0.91 | 1.02 | 0.22 |
| ODI (/h) | 1.03 | 1.003 | 1.05 | 0.03 |
| ODI ≥ 15/h | 1.02 | 1.68 | 2.23 | 0.49 |
| AHI (/h) | 1.02 | 1.003 | 1.04 | 0.02 |
| AHIo (/h) | 1.04 | 1.004 | 1.05 | 0.02 |
| AHIc (/h) | 2.21 | 0.98 | 1.1 | 0.25 |
| 15 ≥ AHI > 30/h | 1.01 | 0.8 | 2.32 | 0.26 |
| AHI ≥ 30/h | 1.32 | 1.22 | 4.02 | 0.009 |
| ASR (/h) | 1.23 | 0.9 | 2.05 | 0.66 |
| ASR ≥ 30/h | 0.86 | 0.53 | 1.02 | 0.91 |
BMI, body mass index; HDLc, high density lipoprotrein cholesterol; LDLc, low density lipoprotein cholesterol; CRP, C-reactive protein; BP, blood pressure; SpO2, oxyhemoglobin saturation; ODI, oxyhemoglobin desaturation index; AHIo, Apnea plus hypopnea index (obstructive mechanism); AHIc, Apnea plus hypopnea index (central mechanism); AHI, AHIc + AHIo; ASR, autonomic sleep-related micro-arousal index. *Body fat mass was measured using dual-energy X-ray absorptiometry. All significant variables are in bold.